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KREMEN1 antibody (Kringle Containing Transmembrane Protein 1) (N-Term)

Details for Product anti-KREMEN1 Antibody No. ABIN357077, Supplier: Log in to see
Antigen
  • AV002070
  • kremem1
  • kremen
  • KREMEN
  • Kremen
  • KREMEN1
  • Krm1
  • KRM1
  • krm1
  • si:ct737139.1
  • si:dkeyp-7c9.1
Alternatives
anti-Human KREMEN1 antibody for Enzyme Immunoassay
Epitope
N-Term
43
19
14
8
3
2
2
2
2
1
Reactivity
Human
70
13
8
2
1
Host
Rabbit
65
5
5
Clonality
Polyclonal
Conjugate
This KREMEN1 antibody is un-conjugated
6
6
6
6
6
6
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
56
56
28
15
5
3
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen.
Isotype Ig
Specificity This antibody detects Kremen at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name Kremen Protein 1 (KREMEN1 Antibody Abstract)
Background Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose
Molecular Weight 63,201 Da
Gene ID 83999
NCBI Accession NP_001034659
UniProt Q96MU8
Pathways WNT Signaling
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-KREMEN1 antibody (Kringle Containing Transmembrane Protein 1) (N-Term) (ABIN357077) anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody
 image for anti-KREMEN1 antibody (Kringle Containing Transmembrane Protein 1) (N-Term) (ABIN357077) anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibody (Image 2)
Background publications Mao, Wu, Davidson, Marhold, Li, Mechler, Delius, Hoppe, Stannek, Walter, Glinka, Niehrs: "Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling." in: Nature, Vol. 417, Issue 6889, pp. 664-7, 2002 (PubMed).

Kammeraat, Veldstra: "Characterization of succinate semialdehyde dehydrogenase from rat brain." in: Biochimica et biophysica acta, Vol. 151, Issue 1, pp. 1-10, 1970 (PubMed).