Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody

Details for Product No. ABIN357395
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms AI836096, cb345, etID36982.3, gfapl, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, GFAP
Epitope
N-Term
(36), (28), (22), (18), (10), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(368), (157), (145), (82), (66), (19), (17), (12), (10), (9), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(238), (208), (23), (10), (4), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(17), (9), (8), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(336), (180), (162), (134), (116), (93), (71), (45), (30), (9), (5), (5), (5), (4), (3), (2), (1), (1)
Pubmed 5 references available
Catalog no. ABIN357395
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GFAP.
Specificity This antibody detects GFAP N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name GFAP
Background GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.
Alternate names: Glial Fibrillary Acidic Protein
Molecular Weight 49880 Da
Gene ID 2670
NCBI Accession NP_001124491
UniProt P14136
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Supplier Images
anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody
anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody (2) anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody (Image 2)
Background publications Nielsen, Holm, Johansen et al.: "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29983-91, 2002 (PubMed).

Lopez-Egido, Cunningham, Berg et al.: "Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity." in: Experimental cell research, Vol. 278, Issue 2, pp. 175-83, 2002 (PubMed).

Namekawa, Takiyama, Aoki et al.: "Identification of GFAP gene mutation in hereditary adult-onset Alexander's disease." in: Annals of neurology, Vol. 52, Issue 6, pp. 779-85, 2002 (PubMed).

Shiroma, Kanazawa, Kato et al.: "Molecular genetic study in Japanese patients with Alexander disease: a novel mutation, R79L." in: Brain & development, Vol. 25, Issue 2, pp. 116-21, 2003 (PubMed).

Quintanar, Franco, Salinas: "Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis." in: Parasitology research, Vol. 90, Issue 4, pp. 261-3, 2003 (PubMed).

Hosts (238), (208), (23), (10), (4), (3), (1)
Reactivities (368), (157), (145), (82), (66), (19), (17), (12), (10), (9), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Applications (336), (180), (162), (134), (116), (93), (71), (45), (30), (9), (5), (5), (5), (4), (3), (2), (1), (1)
Conjugates (17), (9), (8), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (36), (28), (22), (18), (10), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
back to top