You are viewing an incomplete version of our website. Please click to reload the website as full version.

GFAP antibody (Glial Fibrillary Acidic Protein) (N-Term)

Details for Product anti-GFAP Antibody No. ABIN357395, Supplier: Log in to see
Antigen
  • GFAP
  • AI836096
  • cb345
  • etID36982.3
  • gfapl
  • wu:fb34h11
  • wu:fk42c12
  • xx:af506734
  • zgc:110485
Epitope
N-Term
70
69
28
28
23
13
13
6
6
6
5
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
561
215
205
91
89
39
26
24
19
16
11
10
6
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
336
294
27
24
4
3
2
Clonality
Polyclonal
Conjugate
This GFAP antibody is un-conjugated
29
23
19
11
11
11
7
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
483
282
168
165
164
151
70
49
33
21
14
12
11
9
8
7
7
6
5
3
1
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GFAP.
Isotype Ig
Specificity This antibody detects GFAP N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name GFAP (GFAP Antibody Abstract)
Background GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.Synonyms: Glial Fibrillary Acidic Protein
Molecular Weight 49880 Da
Gene ID 2670
NCBI Accession NP_001124491
UniProt P14136
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Pathways
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-GFAP antibody (Glial Fibrillary Acidic Protein) (N-Term) (ABIN357395) anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody
 image for anti-GFAP antibody (Glial Fibrillary Acidic Protein) (N-Term) (ABIN357395) anti-Glial Fibrillary Acidic Protein (GFAP) (N-Term) antibody (Image 2)
Background publications Quintanar, Franco, Salinas: "Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis." in: Parasitology research, Vol. 90, Issue 4, pp. 261-3, 2003 (PubMed).

Shiroma, Kanazawa, Kato et al.: "Molecular genetic study in Japanese patients with Alexander disease: a novel mutation, R79L." in: Brain & development, Vol. 25, Issue 2, pp. 116-21, 2003 (PubMed).

Namekawa, Takiyama, Aoki et al.: "Identification of GFAP gene mutation in hereditary adult-onset Alexander's disease." in: Annals of neurology, Vol. 52, Issue 6, pp. 779-85, 2002 (PubMed).

Lopez-Egido, Cunningham, Berg et al.: "Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity." in: Experimental cell research, Vol. 278, Issue 2, pp. 175-83, 2002 (PubMed).

Nielsen, Holm, Johansen et al.: "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29983-91, 2002 (PubMed).