NEUROD1 antibody (C-Term)

Catalog No. ABIN357406

Product Details anti-NEUROD1 Antibody

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects NeuroD1 at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NeuroD1 protein.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 1,000. Immunoprecipitation 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: NEUROD1 (NEUROD1 Products)

Synonyms: BETA2 antibody, BHF-1 antibody, MODY6 antibody, NEUROD antibody, bHLHa3 antibody, Neurod antibody, neurod antibody, XNeuroD antibody, MGC82572 antibody, NEUROD1 antibody, ND1 antibody, beta2 antibody, bhf-1 antibody, neuro-D antibody, nrd antibody, neuroD antibody, neurod1 antibody, Beta2 antibody, neuronal differentiation 1 antibody, neurogenic differentiation 1 antibody, neuronal differentiation 1 S homeolog antibody, neuronal differentiation 1 L homeolog antibody, NEUROD1 antibody, Neurod1 antibody, neurod1.S antibody, neurod1 antibody, neurod1.L antibody

Background: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.Synonyms: NEUROD, NEUROD1, Neurogenic differentiation factor 1

Molecular Weight: 39890 Da

Gene ID: 4760, 9606

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis