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Antibodies
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anti-Scratch Homolog 1, Zinc Finger Protein (Drosophila) (SCRT1) (C-Term) antibody
Scratch Homolog 1, Zinc Finger Protein (Drosophila) (SCRT1) (C-Term) antibody
| Antigen |
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| Synonyms |
SCRT, DKFZp547F072 |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN357446 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
285.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: SCRT, Transcriptional repressor scratch 1, Scratch homolog 1 zinc finger protein
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Alternative name
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Scratch 1 (SCRT1)
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Gene ID
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83482
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Swiss-Prot
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Q9BWW7
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human SCRATCH1.
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Cross-Reactivity
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Human
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Isotype
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Ig (Matching secondary antibodies)
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Description
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Human SCRT cDNA encodes a protein of 348 amino acids expressed predominantly in thebrain and spinal cord, but also in retina and in neuroendocrine cells of the lung. SCRTexpression by RT-PCR is observed in lung cancers with neuroendocrine features. Thisprotein holds in common with other Snail family members the ability to bind to E-boxenhancer motifs, which are targets of basic helix-loop-helix (bHLH) transcription factors. SCRT impairs heterodimeric proneural bHLH protein achaete-scute homolog-1 and E12,leading to active transcriptional repression at E-box motifs. SCRT has been postulated tofunction in newly differentiating, postmitotic neurons and in cancers with neuroendocrinefeatures by modulating the action of bHLH transcription factors pivotal to neuronaldifferentiation.
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Specificity
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This antibody detects SCRATCH1 at C-term. Species: Human, Mouse. Others not tested. Add. Information: Molecular weight: 35570 Da
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Application Notes
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ELISA 1: 1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.25 mg/ml
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Purification
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Purified
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Buffer
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PBS with 0.09% (W/V) sodium azide
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Storage
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Scratch Homolog 1, Zinc Finger Protein (Drosophila) (SCRT1)", type "Antibodies"
Alternatives 
