GDF1 antibody (N-Term)

Catalog No. ABIN357457

Product Details anti-GDF1 Antibody

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects GDF1 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for GDF1

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Alternative Name: GDF1 (GDF1 Products)

Synonyms: DORV antibody, DTGA3 antibody, AI385651 antibody, Gdf-1 antibody, growth differentiation factor 1 antibody, GDF1 antibody, Gdf1 antibody

Background: GDF1 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right assymetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA which also encodes the longevity assurance gene.Synonyms: Embryonic growth/differentiation factor 1, GDF-1

Molecular Weight: 39502 Da

Gene ID: 2657

NCBI Accession: NP_001483

UniProt: P27539