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UBE2L3 antibody (N-Term)

UBE2L3 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357493
  • Target See all UBE2L3 Antibodies
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    Binding Specificity
    • 15
    • 13
    • 13
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 67
    • 13
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 64
    • 2
    • 1
    Rabbit
    Clonality
    • 64
    • 3
    Polyclonal
    Conjugate
    • 29
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2L3 antibody is un-conjugated
    Application
    • 62
    • 37
    • 27
    • 13
    • 13
    • 12
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific to UBE2L3/UBCH7 (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE2L3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product UBE2L3 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    Alternative Name
    UBE2L3 / UBCH7 (UBE2L3 Products)
    Synonyms
    E2-F1 antibody, L-UBC antibody, UBCH7 antibody, UbcM4 antibody, C79827 antibody, Ubce7 antibody, ube2l3 antibody, wu:fc22h11 antibody, zgc:86727 antibody, UBE2L3 antibody, ube2l3l antibody, wu:fb38h03 antibody, ubiquitin conjugating enzyme E2 L3 antibody, ubiquitin-conjugating enzyme E2L 3 antibody, ubiquitin-conjugating enzyme E2L 3a antibody, ubiquitin conjugating enzyme E2 L3 S homeolog antibody, ubiquitin-conjugating enzyme E2L 3b antibody, UBE2L3 antibody, Ube2l3 antibody, ube2l3a antibody, ube2l3.S antibody, ube2l3b antibody
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.Synonyms: E2-F1, L-UBC, UBCE7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2 L3, Ubiquitin-protein ligase L3
    Molecular Weight
    17861 Da
    Gene ID
    7332, 5874
    UniProt
    P68036
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