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Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody

Details for Product No. ABIN357707, Supplier: Log in to see
Antigen
  • A530043O15Rik
  • D030046F19
  • DDBDRAFT_0189115
  • DDBDRAFT_0237846
  • DDB_0189115
  • DDB_0237846
  • F2N1.21
  • F2N1_21
  • Face-1
  • FACE-1
  • FACE1
  • fi45a02
  • HGPS
  • MADB
  • PRO1
  • STE24
  • Ste24p
  • wu:fi45a02
  • zgc:55655
Epitope
Middle Region
58
15
15
14
14
13
9
2
2
2
1
Reactivity
Human, Mouse (Murine)
107
25
14
9
1
1
Host
Rabbit
92
15
Clonality
Polyclonal
Conjugate
Un-conjugated
11
7
7
7
6
6
3
3
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
101
56
26
8
8
6
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZMPSTE24.
Isotype Ig
Specificity This antibody is specific to ZMPSTE24 (Center).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ZMPSTE24 (Zmpste24 Antibody Abstract)
Background ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.Synonyms: CAAX prenyl protease 1 homolog, FACE-1, FACE1, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, STE24, Zinc metalloproteinase Ste24 homolog
Molecular Weight 54813 Da
Gene ID 10269, 5874
UniProt O75844
Research Area Proteolysis / Ubiquitin, Cytoskeleton
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. (See Ref.1)Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody (ABIN357707) anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody
 image for anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody (ABIN357707) anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody (Image 2)
Background publications Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, 2005 (PubMed).