ADCY2 antibody (Adenylate Cyclase 2 (Brain)) (C-Term)

Details for Product anti-ADCY2 Antibody No. ABIN357898, Supplier: Log in to see
Antigen
  • ADCY2
  • mKIAA1060
  • AC2
  • HBAC2
  • adenylate cyclase 2
  • adenylate cyclase 2 (brain)
  • ADCY2
  • Adcy2
Alternatives
anti-Human ADCY2 antibody for Confocal Microscopy
Epitope
C-Term
6
5
5
4
4
3
3
2
2
2
2
1
Reactivity
Human
42
6
5
2
2
2
1
1
Host
Rabbit
38
4
Clonality
Polyclonal
Conjugate
This ADCY2 antibody is un-conjugated
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
17
8
7
5
3
2
2
2
1
1
1
Options
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ADCY2.
Isotype Ig
Specificity This antibody detects Adenylate Cyclase 2 (ADCY2) (C-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Adenylate Cyclase Type 2 (ADCY2 Antibody Abstract)
Background ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.Synonyms: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060
Molecular Weight 123603 Da
Gene ID 108, 9606
UniProt Q08462
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-ADCY2 antibody (Adenylate Cyclase 2 (Brain)) (C-Term) (ABIN357898) anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody
 image for anti-ADCY2 antibody (Adenylate Cyclase 2 (Brain)) (C-Term) (ABIN357898) anti-Adenylate Cyclase 2 (Brain) (ADCY2) (C-Term) antibody (Image 2)
Background publications Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Ludwig, Seuwen: "Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms." in: Journal of receptor and signal transduction research, Vol. 22, Issue 1-4, pp. 79-110, 2002 (PubMed).