AASS antibody (Middle Region)

Catalog No. ABIN357942

Product Details anti-AASS Antibody

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASS antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects AASS (Center).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human AASS.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AASS

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Alternative Name: AASS (AASS Products)

Synonyms: LKR/SDH antibody, LKRSDH antibody, LORSDH antibody, LKR antibody, LOR antibody, LOR/SDH antibody, Lorsdh antibody, SDH antibody, aminoadipate-semialdehyde synthase antibody, AASS antibody, Aass antibody

Background: AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.Synonyms: Alpha-aminoadipic semialdehyde synthase, LKR/SDH, mitochondrial

Molecular Weight: 102001 Da

Gene ID: 10157, 9606

UniProt: Q9UDR5

Pathways: SARS-CoV-2 Protein Interactome