ITGB1BP3 antibody (N-Term)

Catalog No. ABIN357956

Product Details anti-ITGB1BP3 Antibody

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1BP3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ITGB1BP3 (N-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human ITGB1BP3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ITGB1BP3

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Alternative Name: ITGB1BP3 / NRK2 (ITGB1BP3 Products)

Synonyms: ITGB1BP3 antibody, MIBP antibody, NRK2 antibody, itgb1bp3 antibody, 2310015C21Rik antibody, Itgb1bp3 antibody, Mibp antibody, zgc:103408 antibody, nicotinamide riboside kinase 2 antibody, integrin beta 1 binding protein 3 antibody, nicotinamide riboside kinase 2 S homeolog antibody, NMRK2 antibody, ITGB1BP3 antibody, nmrk2.S antibody, nmrk2 antibody, Nmrk2 antibody

Background: ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.Synonyms: Integrin beta-1-binding protein 3, MIBP, Muscle integrin-binding protein, Nicotinamide riboside kinase 2, Nicotinic acid riboside kinase 2, NmR-K2, RNK2, Ribosylnicotinamide kinase 2, Ribosylnicotinic acid kinase 2

Molecular Weight: 26046 Da

Gene ID: 27231, 9606

UniProt: Q9NPI5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development