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Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody

Details for Product No. ABIN358008, Supplier: Log in to see
Antigen
  • 23.m05913
  • H-2Ke2
  • H2-KE2
  • h2-ke2
  • HKE2
  • hke2
  • KE-2
  • Ke-2
  • ke-2
  • Ke2
  • PFD6
  • pfd6
  • pfdn6
  • Pfdn6
  • pfdn6a
  • pfdn6b
  • zgc:66282
Epitope
C-Term, N-Term
11
3
2
2
1
Reactivity
Human
19
4
4
3
1
1
1
Host
Rabbit
15
4
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
16
6
4
4
3
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PFDN6.
Isotype Ig
Specificity This antibody detects PFDN6 (N-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PFDN6 / HKE2 (PFDN6 Antibody Abstract)
Background PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.Synonyms: Ke2, PFD6, Prefoldin subunit 6
Molecular Weight 14583 Da
Gene ID 10471, 9606
UniProt O15212
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody (ABIN358008) anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody
Background publications Ostrov, Barnes, Smith, Binns, Brusko, Brown, Quint, Litherland, Roopenian, Iczkowski: "Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex." in: Tissue antigens, Vol. 69, Issue 2, pp. 181-8, 2007 (PubMed).

Simons, Staes, Rommelaere, Ampe, Lewis, Cowan: "Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4196-203, 2004 (PubMed).

Vainberg, Lewis, Rommelaere, Ampe, Vandekerckhove, Klein, Cowan: "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin." in: Cell, Vol. 93, Issue 5, pp. 863-73, 1998 (PubMed).