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CDK1 antibody (Cyclin-Dependent Kinase 1) (pThr161)

Details for Product anti-CDK1 Antibody No. ABIN358102, Supplier: Log in to see
Antigen
  • 5363
  • CDC2
  • CDCDm
  • CDK1
  • CDK1/CDC2
  • CG5363
  • Cdc2
  • Cdk-1
  • Cdk1
  • Dcdc2
  • Dm cdc2
  • DmCdc2
  • DmCdk1
  • Dmcdc2
  • Dmel\\CG5363
  • cdc
  • cdc2Dm
  • cdk1
  • dCdk1
  • group 4
  • l(2)31Eh
  • CDC28A
  • P34CDC2
  • Cdc2a
  • p34
  • cdc2
  • wu:fc30e01
  • zgc:92032
  • PSTAIR
  • cdc-2
  • cdc2-a
  • cdc28a
  • cdc2x1.1
  • p34cdc2
  • xcdc2
  • CDC2A
  • CDC2AAT
  • CDK2
  • CDKA1
  • CDKA;1
  • CYCLIN-DEPENDENT KINASE A;1
  • cell division control 2
  • POL3
  • pold
Alternatives
anti-Human CDK1 antibody for Immunocytochemistry
Epitope
pThr161
89
69
46
32
28
27
19
18
15
14
14
14
14
14
8
8
6
5
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
589
255
224
25
23
21
16
10
6
5
5
5
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
484
141
Clonality
Polyclonal
Conjugate
This CDK1 antibody is un-conjugated
25
21
18
14
13
13
6
5
5
5
5
5
5
5
5
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
498
224
157
98
89
69
57
33
31
14
10
10
7
6
6
2
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T161 of human CDC2.
Isotype Ig
Specificity This antibody detects CDC2 pThr161.
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CDK1 (CDK1 Antibody Abstract)
Background CDC2 (CDK3) complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in cell cycle control. CDK3 can phosphorylate histone H1 and interacts with an unknown type of cyclin.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase
Molecular Weight 35046 Da
Gene ID 983, 9606
UniProt P06493
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-CDK1 antibody (Cyclin-Dependent Kinase 1) (pThr161) (ABIN358102) anti-Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody
 image for anti-CDK1 antibody (Cyclin-Dependent Kinase 1) (pThr161) (ABIN358102) anti-Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody (Image 2)
Background publications Ren, Rollins: "Cyclin C/cdk3 promotes Rb-dependent G0 exit." in: Cell, Vol. 117, Issue 2, pp. 239-51, 2004 (PubMed).

Bullrich, MacLachlan, Sang et al.: "Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer." in: Cancer research, Vol. 55, Issue 6, pp. 1199-205, 1995 (PubMed).