CD131 antibody (pTyr766)

Catalog No. ABIN358147

Product Details anti-CD131 Antibody

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Binding Specificity: pTyr766

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD131 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects IL3R pTyr766.

Purification: Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y766 of human IL3R.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Dot Blot: 1/500. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CD131

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Alternative Name: CD131 / CSF2RB (CSF2RB Products)

Synonyms: Csf2rb1 antibody, CSF2RB antibody, cd131 antibody, cdw131 antibody, il3rb antibody, il5rb antibody, il-3rbc antibody, CD131 antibody, CDw131 antibody, IL3RB antibody, IL5RB antibody, SMDP5 antibody, AI848964 antibody, AIC2B antibody, Bc antibody, Csfgmrb antibody, Il3r antibody, Il3rb antibody, Il3rb1 antibody, Il5rb antibody, colony stimulating factor 2 receptor beta common subunit antibody, colony stimulating factor 2 receptor beta common subunit S homeolog antibody, cytokine receptor common subunit beta-like antibody, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) antibody, CSF2RB antibody, Csf2rb antibody, csf2rb.S antibody, CRCBL antibody, csf2rb antibody

Background: IL3R (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective IL3R has been reported to be associated with protein alveolar proteinosis (PAP). PAP is an autosomal recessive fatal respiratory disease.Synonyms: Cytokine receptor common subunit beta, GM-CSF-RB, GM-CSF/IL-3/IL-5 receptor common beta-chain, IL3RB, IL5RB

Molecular Weight: 97336 Da

Gene ID: 1439, 9606

UniProt: P32927

Pathways: JAK-STAT Signaling