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Platelet-Derived Growth Factor Receptor alpha (PDGFA) (pTyr762) antibody

Antigen

Platelet-Derived Growth Factor Receptor alpha (PDGFA)

Synonyms PDGF1, PDGF-A, CD140A, PDGFR2, MGC74795, RHEPDGFRA, CD140a, Pdgfr-2, AI115593, PDGFRA, pdgfa, zgc:100777, pdgfra, MGC52594, PDGFR, PDGFR-A, PDGFA, pdgf, pdgf1, pdgf-a
Epitope
Alternatives

pTyr762

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Enzyme Immunoassay (EIA)
Catalog no. ABIN358298
Quantity 0.1 mg  (0.25 mg/ml)
Price 285.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A
Alternative name CD140a / PDGFRA
Gene ID 5156
Swiss-Prot P16234
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticphosphopeptide corresponding to amino acid residues surrounding Y762 of humanPDGFRA.
Cross-Reactivity Human
Isotype Ig  (Matching secondary antibodies)
Description PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derivedgrowth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether thefunctional receptor is a homodimer or a heterodimer, composed of both platelet-derivedgrowth factor receptor alpha and beta polypeptides. Studies in knockout mice, wherehomozygosity is lethal, indicate that the alpha form of the platelet-derived growth factorreceptor is particularly important for kidney development since mice heterozygous for thereceptor exhibit defective kidney phenotypes.
Specificity This antibody detects PDGFRA pTyr762. Predicted to cross react with Mouse (100% Antigen Homology). Species: Human. Others not tested. Add. Information: Molecular weight: 122688 Da

Application Details

Application Notes ELISA: 1/1,000. Dot Blot: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.25 mg/ml
Purification Aff - Purified
Buffer PBS with 0.09% (W/V) Sodium Azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Platelet-Derived Growth Factor Receptor alpha (PDGFA)", type "Antibodies"
Hosts Rabbit (55), Mouse (20), Rat (8), Goat (1)
Reactivities Human (72), Mouse (Murine) (12), Rat (Rattus) (6)
Applications Western Blotting (WB) (40), Enzyme Immunoassay (EIA) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Flow Cytometry (FACS) (18), Dot Blot (Dot) (12), ELISA (12), Immunohistochemistry (IHC) (6), Immunofluorescence (IF) (5), ELISA (Detection) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunocytochemistry (ICC) (1)
Conjugates APC (4), Biotin (4), PE (3), CF (1), FITC (1)
Epitopes C-Term E1063 (1), Y1018 (1), Y574 (1), Y762 (1), pTyr1018 (1), pTyr572 (1), pTyr574 (1), pTyr762 (1), pY572 (1), pY754 (1), pY988 (1)