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Platelet-Derived Growth Factor Receptor alpha (PDGFA) (pTyr1018) antibody
| Antigen | Platelet-Derived Growth Factor Receptor alpha (PDGFA) |
| Synonyms | PDGF1, PDGF-A, CD140A, PDGFR2, MGC74795, RHEPDGFRA, CD140a, Pdgfr-2, AI115593, PDGFRA, pdgfa, zgc:100777, pdgfra, MGC52594, PDGFR, PDGFR-A, PDGFA, pdgf, pdgf1, pdgf-a |
| Epitope |
 Alternatives pTyr1018 |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Enzyme Immunoassay (EIA)
|
| Catalog no. | ABIN358299 |
| Quantity | 0.1 mg (0.25 mg/ml) |
| Price | 285.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A |
| Alternative name | CD140a / PDGFRA |
| Gene ID | 5156 |
| Swiss-Prot | P16234 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated syntheticphosphopeptide corresponding to amino acid residues surrounding Y1018 of humanPDGFRA. |
| Cross-Reactivity | Human |
| Isotype | Ig (Matching secondary antibodies) |
| Description | PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derivedgrowth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether thefunctional receptor is a homodimer or a heterodimer, composed of both platelet-derivedgrowth factor receptor alpha and beta polypeptides. Studies in knockout mice, wherehomozygosity is lethal, indicate that the alpha form of the platelet-derived growth factorreceptor is particularly important for kidney development since mice heterozygous for thereceptor exhibit defective kidney phenotypes. |
| Specificity | This antibody detects PDGFRA pTyr1018. Predicted to cross react with Mouse and Zebrafish (100% Antigen Homology). Species: Human. Others not tested. Add. Information: Molecular weight: 122688 Da |
Application Details
| Application Notes | ELISA: 1/1,000. Dot Blot: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 0.25 mg/ml |
| Purification | Aff - Purified |
| Buffer | PBS with 0.09% (W/V) Sodium Azide as preservative. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Platelet-Derived Growth Factor Receptor alpha (PDGFA)", type "Antibodies"
| Hosts | Rabbit (55), Mouse (20), Rat (8), Goat (1) |
| Reactivities | Human (72), Mouse (Murine) (12), Rat (Rattus) (6) |
| Applications | Western Blotting (WB) (40), Enzyme Immunoassay (EIA) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Flow Cytometry (FACS) (18), Dot Blot (Dot) (12), ELISA (12), Immunohistochemistry (IHC) (6), Immunofluorescence (IF) (5), ELISA (Detection) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunocytochemistry (ICC) (1) |
| Conjugates | APC (4), Biotin (4), PE (3), CF (1), FITC (1) |
| Epitopes | C-Term E1063 (1), Y1018 (1), Y574 (1), Y762 (1), pTyr1018 (1), pTyr572 (1), pTyr574 (1), pTyr762 (1), pY572 (1), pY754 (1), pY988 (1) |
