Did you know that you can buy products from over 140 different suppliers from us?

Glial Fibrillary Acidic Protein (GFAP) (pSer8) antibody

Details for Product No. ABIN358488
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AI836096, cb345, etID36982.3, gfapl, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, GFAP
Epitope
pSer8
(72), (45), (23), (22), (14), (10), (6), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(432), (153), (146), (80), (64), (18), (17), (12), (10), (9), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(275), (230), (24), (10), (3), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(20), (15), (14), (8), (8), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Application
ELISA
(386), (208), (178), (170), (115), (113), (71), (42), (30), (11), (5), (5), (5), (4), (3), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN358488
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the ?-terminal region of human Phospho-GFAP-Ser8.
Specificity This antibody detects GFAP pSer8.
Purification Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Alternative Name GFAP
Background GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.
Alternate names: Glial Fibrillary Acidic Protein
Molecular Weight 49880 Da
Gene ID 2670
NCBI Accession NP_001124491
UniProt P14136
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Application Notes ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Glial Fibrillary Acidic Protein (GFAP) (pSer8) antibody anti-Glial Fibrillary Acidic Protein (GFAP) (pSer8) antibody
Background publications Nielsen, Holm, Johansen et al.: "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29983-91, 2002 (PubMed).

Lopez-Egido, Cunningham, Berg et al.: "Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity." in: Experimental cell research, Vol. 278, Issue 2, pp. 175-83, 2002 (PubMed).

Namekawa, Takiyama, Aoki et al.: "Identification of GFAP gene mutation in hereditary adult-onset Alexander's disease." in: Annals of neurology, Vol. 52, Issue 6, pp. 779-85, 2002 (PubMed).

Shiroma, Kanazawa, Kato et al.: "Molecular genetic study in Japanese patients with Alexander disease: a novel mutation, R79L." in: Brain & development, Vol. 25, Issue 2, pp. 116-21, 2003 (PubMed).

Quintanar, Franco, Salinas: "Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis." in: Parasitology research, Vol. 90, Issue 4, pp. 261-3, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN358488
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
Did you look for something else?
back to top