HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (pTyr361)

Details for Product anti-HIPK2 Antibody No. ABIN358542, Supplier: Log in to see
Antigen
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • HIPK2
  • hipk2
  • Hipk2
Alternatives
anti-Human HIPK2 antibody for Dot Blot
Epitope
pTyr361
17
16
13
11
10
7
4
3
3
2
1
1
1
1
1
1
Reactivity
Human
96
12
8
3
2
2
2
2
2
1
1
1
1
Host
Rabbit
83
13
Clonality
Polyclonal
Conjugate
This HIPK2 antibody is un-conjugated
8
8
8
8
8
4
Application
Enzyme Immunoassay (EIA)
64
60
36
16
14
4
3
3
3
1
Options
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y361 of human HIPK2.
Isotype Ig
Specificity This antibody reacts to HIPK2 pTyr361.
Purification Protein A column, followed by two-step phosphospecific peptide affinity purification
Alternative Name HIPK2 (HIPK2 Antibody Abstract)
Background HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.Synonyms: Homeodomain-interacting protein kinase 2
Gene ID 28996, 9606
UniProt Q9H2X6
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Pathways Cell Division Cycle
Application Notes ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (pTyr361) (ABIN358542) anti-Homeodomain Interacting Protein Kinase 2 (HIPK2) (pTyr361) antibody
Background publications Guha, Chaerkady, Marimuthu, Patterson, Kashyap, Harsha, Sato, Bader, Lash, Minna, Pandey, Varmus: "Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 37, pp. 14112-7, 2008 (PubMed).

Guo, Villén, Kornhauser, Lee, Stokes, Rikova, Possemato, Nardone, Innocenti, Wetzel, Wang, MacNeill, Mitchell, Gygi, Rush, Polakiewicz, Comb: "Signaling networks assembled by oncogenic EGFR and c-Met." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 692-7, 2008 (PubMed).

Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Product cited in: Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).