ABCB5 antibody (N-Term)

Catalog No. ABIN358601

Product Details anti-ABCB5 Antibody

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes ABCB5 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ABCB5.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50-1/100. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ABCB5

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Alternative Name: ABCB5 (ABCB5 Products)

Synonyms: ABCB5alpha antibody, ABCB5beta antibody, EST422562 antibody, 9230106F14Rik antibody, RGD1566342 antibody, ABCB5 antibody, mdr1 antibody, im:7158730 antibody, wu:fc18f02 antibody, wu:fi81f06 antibody, ATP binding cassette subfamily B member 5 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antibody, ATP-binding cassette sub-family B member 5 antibody, ABCB5 antibody, Abcb5 antibody, abcb5 antibody, TGME49_249820 antibody, PAAG_04387 antibody, VDBG_00160 antibody, VDBG_02292 antibody

Background: ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.Synonyms: ATP-binding cassette sub-family B member 5

Molecular Weight: 89831 Da

Gene ID: 340273, 9606

UniProt: Q2M3G0