SIRT5 antibody (C-Term)

Catalog No. ABIN358734

Product Details anti-SIRT5 Antibody

Target: SIRT5 (Sirtuin 5 (SIRT5))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes SIRT5 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from C-terminal region of human Sirt5.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5 (SIRT5 Products)

Synonyms: SIR2L5 antibody, 0610012J09Rik antibody, 1500032M05Rik antibody, AV001953 antibody, zgc:92288 antibody, sirt5-a antibody, SIRT5 antibody, sir2l5 antibody, sirtuin 5 antibody, sirtuin 5 L homeolog antibody, SIRT5 antibody, Sirt5 antibody, sirt5 antibody, sirt5.L antibody, CC1G_00083 antibody

Background: SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.Synonyms: NAD-dependent deacetylase sirtuin-5, SIR2-like protein 5, SIR2L5, SIRT-5, sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), sirtuin 5, sirtuin type 5, sirtuin-5

Gene ID: 23408, 9606

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome