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Sirtuin 7 (SIRT7) (C-Term) antibody

Details for Product No. ABIN358736, Supplier: Log in to see
Antigen
  • SIRT7
  • LOC796135
  • SIR2L7
Epitope
C-Term
32
13
10
8
5
5
5
4
4
3
3
2
2
1
1
1
Reactivity
Human
96
51
38
5
4
2
Host
Rabbit
97
6
6
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
84
45
30
18
11
10
7
6
4
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Sirt7.
Isotype Ig
Specificity This antibody reacts to SIRT7.
Purification Purified
Alternative Name SIRT7 (SIRT7 Antibody Abstract)
Background SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.Synonyms: NAD-dependent deacetylase sirtuin-7, S.cerevisiae, SIR2-like protein 7, SIR2L7, SIRT-7, homolog) 7, sirtuin (silent mating type information regulation 2, sirtuin 7, sirtuin type 7, sirtuin-7
Gene ID 51547, 9606
UniProt Q9NRC8
Research Area Cancer, Chromatin Binding Proteins, Transcription Factors, Proteases
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Sirtuin 7 (SIRT7) (C-Term) antibody (ABIN358736) anti-Sirtuin 7 (SIRT7) (C-Term) antibody
 image for anti-Sirtuin 7 (SIRT7) (C-Term) antibody (ABIN358736) anti-Sirtuin 7 (SIRT7) (C-Term) antibody (Image 2)
Background publications Frye: "Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins." in: Biochemical and biophysical research communications, Vol. 273, Issue 2, pp. 793-8, 2000 (PubMed).