Kallikrein 2 antibody (C-Term)

Catalog No. ABIN358874

Product Details anti-Kallikrein 2 Antibody

Target: Kallikrein 2 (KLK2)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Kallikrein 2 (KLK2).

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Kallikrein 2

Target: Kallikrein 2 (KLK2)

Alternative Name: KLK2 / Kallikrein-2 (KLK2 Products)

Synonyms: KLK2A2 antibody, hGK-1 antibody, hK2 antibody, KLK2 antibody, Ton antibody, rGK-2 antibody, Klk2 antibody, kallikrein related peptidase 2 antibody, kallikrein-related peptidase 2 antibody, kallikrein-2 antibody, kallikrein 1-related peptidase C2 antibody, KLK2 antibody, LOC748637 antibody, Klk1c2 antibody, LOC100716976 antibody

Background: Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.Synonyms: Glandular kallikrein-1, Kallikrein 2, Kallikrein2, Tissue kallikrein-2, hGK-1, hK2

Gene ID: 3817

NCBI Accession: NP_001002231

UniProt: P20151

Pathways: Complement System