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RIPK3 antibody (Middle Region)

RIPK3 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359363
  • Target See all RIPK3 Antibodies
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Binding Specificity
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 79
    • 42
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    Human, Mouse
    Host
    • 82
    • 9
    Rabbit
    Clonality
    • 82
    • 9
    Polyclonal
    Conjugate
    • 46
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK3 antibody is un-conjugated
    Application
    • 84
    • 52
    • 44
    • 18
    • 11
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects RIPK3 / RIP3.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human RIPK3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RIPK3 Primary Antibody
  • Application Notes
    ELISA1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Alternative Name
    RIPK3 / RIP3 (RIPK3 Products)
    Synonyms
    RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
    Background
    The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
    Molecular Weight
    56901 Da.
    Gene ID
    11035, 9606
    UniProt
    Q9Y572
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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