LINGO1 antibody (N-Term)

Catalog No. ABIN359531

Product Details anti-LINGO1 Antibody

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects LINGO1 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LRRN6A.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO1 (LINGO1 Products)

Synonyms: lern1 antibody, lrrn6a antibody, unq201 antibody, DKFZp459P0736 antibody, LERN1 antibody, LRRN6A antibody, UNQ201 antibody, 4930471K13Rik antibody, AV148400 antibody, LINGO-1 antibody, Lrrn6a antibody, leucine rich repeat and Ig domain containing 1 antibody, LINGO1 antibody, lingo1 antibody, Lingo1 antibody

Background: LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.Synonyms: LERN1, LINGO1, LRRN6A, Leucine-rich repeat and immunoglobilin-domain containing protein 1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A

Molecular Weight: 69876 Da

Gene ID: 84894, 9606

UniProt: Q96FE5