Cyclin A2 (CCNA2) (C-Term) antibody

Details for Product No. ABIN359545
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Antigen
Synonyms ccn1, ccna, ccna1, CCN1, CCNA, AA408589, Ccn-1, Ccn1, Ccna, CycA2, Cyca, cb671, chunp6924, wu:fi36f03, CYCA, Cyclin-A2, ccna2, Cyclin-A, cyclinA
Epitope
C-Term
(19), (15), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(117), (50), (38), (26), (5), (4), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(88), (54), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(114), (48), (36), (31), (30), (26), (17), (10), (8), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN359545
357.50 $
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CCNA2.
Specificity This antibody reacts to CCNA2.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name Cyclin A2
Background CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Alternate names: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
Gene ID 890, 9606
UniProt P20248
Research Area Cell Cycle
Application Notes ELISA: 1/1,000. Western Blot. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Wang, Chenivesse, Henglein et al.: "Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma." in: Nature, Vol. 343, Issue 6258, pp. 555-7, 1990 (PubMed).

Henglein, Chenivesse, Wang et al.: "Structure and cell cycle-regulated transcription of the human cyclin A gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5490-4, 1994 (PubMed).

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