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ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) antibody

Antigen

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13)

Synonyms Gm710, vWF-CP, ADAMTS13, TTP, VWFCP, C9orf8, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, PRO4389, MGC126403, FLJ16363, FLJ32769, AI605170, ADAMTS-12, ADAMTS12
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Catalog no. ABIN359601
Quantity 0.1 mg  (0.25 mg/ml)
Price 285.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: ADAMTS-13, ADAM-TS13, C9orf8, vWF-cleaving protease, A disintegrin andmetalloproteinase with thrombospondin motifs 13, von Willebrand factor-cleaving protease
Alternative name ADAMTS13
Gene ID 11093
Swiss-Prot Q76LX8
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide between 836~866 amino acids from the center region of Human ADAMTS13.
Cross-Reactivity Human
Isotype Ig  (Matching secondary antibodies)
Description ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase withthrombospondin motif) protein family. Members of the family share several distinct proteinmodules, including a propeptide region, a metalloproteinase domain, a disintegrin-likedomain, and a thrombospondin type 1 (TS) motif. Individual members of this family differin the number of C-terminal TS motifs, and some have unique C-terminal domains. Theenzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible forcleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme isassociated with thrombotic thrombocytopenic purpura.
Specificity This antibody recognizes ADAMTS13. Species: Human. Others not tested. Add. Information: Calculated MW: 153604 Da

Application Details

Application Notes ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.25 mg/ml
Purification Aff - Purified
Buffer PBS with 0.09% (W/V) Sodium Azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Research Area Proteolysis / Ubiquitin, Metalloprotease, Extracellular Matrix, Coagulation
Restrictions For Research Use only

Alternatives

Alternatives for antigen "ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13)", type "Antibodies"
Hosts Rabbit (41), Mouse (4)
Reactivities Human (45), Mouse (Murine) (38), Rat (Rattus) (6), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Rabbit (1)
Applications Flow Cytometry (FACS) (36), Immunofluorescence (IF) (36), Western Blotting (WB) (9), ELISA (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunoprecipitation (IP) (4), Enzyme Immunoassay (EIA) (3), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (IHC) (1)
Conjugates Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes Center (1)