MAPK4 antibody (C-Term)

Catalog No. ABIN359633

Product Details anti-MAPK4 Antibody

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ERK4.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK4.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAPK4

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Alternative Name: MAPK4 / ERK4 (MAPK4 Products)

Synonyms: ERK-4 antibody, ERK3 antibody, Erk4 antibody, MAPK 4 antibody, PRKM4 antibody, p63MAPK antibody, A330097D03Rik antibody, Erk3 antibody, Prkm4 antibody, p63Mapk antibody, erk4 antibody, wu:fi27d11 antibody, zgc:55498 antibody, ATMPK4 antibody, F2N1.1 antibody, F2N1_1 antibody, MAP kinase 4 antibody, mitogen-activated protein kinase 4 antibody, MAP kinase 4 antibody, MAPK4 antibody, Mapk4 antibody, mapk4 antibody, MPK4 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.Synonyms: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK

Gene ID: 5596, 9606

UniProt: P31152

Pathways: MAPK Signaling