CXCL7 antibody (C-Term)

Catalog No. ABIN359713

Product Details anti-CXCL7 Antibody

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Binding Specificity: AA 99-128, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes PBP (PPBP).

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99~128 amino acids from the C-term of Human PPBP.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CXCL7

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Alternative Name: NAP2 / PPBP / CXCL7 (PPBP Products)

Synonyms: 2400003M24Rik antibody, AI854500 antibody, CTAP3 antibody, CTAPIII antibody, Cxcl7 antibody, LA-PF4 antibody, LDGF antibody, MDGF antibody, NAP-2 antibody, NAP-2-L1 antibody, Scyb7 antibody, TGB antibody, TGB1 antibody, THBGB1 antibody, b-TG1 antibody, beta-TG antibody, B-TG1 antibody, Beta-TG antibody, CTAP-III antibody, CXCL7 antibody, PBP antibody, SCYB7 antibody, TC1 antibody, TC2 antibody, THBGB antibody, Nap-2 antibody, CTAPIII/NAP-2 antibody, Platelet basic protein antibody, pro-platelet basic protein antibody, scyb7 antibody, Ppbp antibody, PPBP antibody

Background: PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.Synonyms: C-X-C motif chemokine 7, CTAP3, Leukocyte-derived growth factor, Macrophage-derived growth factor, SCYB7, Small-inducible cytokine B7, TGB1, THBGB1

Gene ID: 5473, 9606

UniProt: P02775