You are viewing an incomplete version of our website. Please click to reload the website as full version.

IRAK2 antibody (Interleukin-1 Receptor-Associated Kinase 2) (N-Term)

Details for Product anti-IRAK2 Antibody No. ABIN360117, Supplier: Log in to see
Antigen
  • IRAK-2
  • 6330415L08Rik
  • AI649099
Alternatives
anti-Human IRAK2 antibody for Immunofluorescence
Epitope
N-Term
73
19
15
14
9
8
7
6
5
5
5
3
3
2
2
2
2
1
1
Reactivity
Human
177
38
22
Host
Rabbit
170
27
Clonality
Polyclonal
Conjugate
This IRAK2 antibody is un-conjugated
10
10
7
6
6
6
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
172
108
35
31
22
14
11
8
5
4
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human IRAK2.
Isotype Ig
Specificity This antibody reacts to IRAK2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name IRAK2 (IRAK2 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.Synonyms: IRAK-2, Interleukin-1 receptor-associated kinase-like 2
Gene ID 3656, 9606
UniProt O43187
Research Area Immunology, Innate Immunity, Cytokines, Receptors, Inflammation
Pathways TLR Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-IRAK2 antibody (Interleukin-1 Receptor-Associated Kinase 2) (N-Term) (ABIN360117) anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (N-Term) antibody
Background publications Muzio, Ni, Feng et al.: "IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling." in: Science (New York, N.Y.), Vol. 278, Issue 5343, pp. 1612-5, 1997 (PubMed).