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IRAK2 antibody (C-Term)

IRAK2 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360118
  • Target See all IRAK2 Antibodies
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    Binding Specificity
    • 18
    • 15
    • 8
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 86
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 87
    • 3
    Rabbit
    Clonality
    • 78
    • 12
    Polyclonal
    Conjugate
    • 39
    • 8
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK2 antibody is un-conjugated
    Application
    • 65
    • 48
    • 23
    • 14
    • 14
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to IRAK2.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IRAK2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IRAK2 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    Alternative Name
    IRAK2 (IRAK2 Products)
    Synonyms
    IRAK-2 antibody, 6330415L08Rik antibody, AI649099 antibody, interleukin 1 receptor associated kinase 2 antibody, interleukin-1 receptor-associated kinase 2 antibody, IRAK2 antibody, Irak2 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.Synonyms: IRAK-2, Interleukin-1 receptor-associated kinase-like 2
    Gene ID
    3656, 9606
    UniProt
    O43187
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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