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PHLPP1 antibody (N-Term)

PHLPP1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360194
  • Target See all PHLPP1 Antibodies
    PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 31
    • 13
    • 12
    Human
    Host
    • 31
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHLPP1 antibody is un-conjugated
    Application
    • 14
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PHLPP1.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHLPP1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PHLPP1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
    Alternative Name
    PHLPP1 (PHLPP1 Products)
    Synonyms
    PHLPP antibody, PLEKHE1 antibody, SCOP antibody, AI836256 antibody, Phlpp antibody, Plekhe1 antibody, mKIAA0606 antibody, Scop antibody, PH domain and leucine rich repeat protein phosphatase 1 antibody, PHLPP1 antibody, phlpp1 antibody, Phlpp1 antibody
    Background
    PHLPP1 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes.Synonyms: KIAA0606, PH domain leucine-rich repeat-containing protein phosphatase 1, PHLPP, PLEKHE1, Pleckstrin homology domain-containing family E member 1, SCOP, Suprachiasmatic nucleus circadian oscillatory protein
    Gene ID
    23239, 9606
    UniProt
    O60346
    Pathways
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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