GARS antibody (C-Term)

Catalog No. ABIN360353

Product Details anti-GARS Antibody

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to GARS.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GARS.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Alternative Name: Glycyl-tRNA Synthetase (GARS Products)

Synonyms: CMT2D antibody, DSMAV antibody, GlyRS antibody, HMN5 antibody, SMAD1 antibody, Aat-gly antibody, CG6778 antibody, Dmel\\CG6778 antibody, GRS antibody, gars antibody, team antibody, RGD1559871 antibody, GENA202 antibody, Gena201 antibody, Nmf249 antibody, Sgrp23 antibody, GB13467 antibody, MGC79495 antibody, fb02f03 antibody, si:dkey-276i5.1 antibody, wu:fb02f03 antibody, NI36_08435 antibody, glycyl-tRNA synthetase antibody, Glycyl-tRNA synthetase antibody, glycine--tRNA ligase antibody, glycyl-tRNA synthetase L homeolog antibody, Glycine--tRNA ligase antibody, GARS antibody, GlyRS antibody, Gars antibody, LOC408392 antibody, gars.L antibody, gars antibody, LOC692991 antibody, glyQ antibody, TTHA0543 antibody, NI36_RS08405 antibody

Background: GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.Synonyms: AP-4-A synthetase, Diadenosine tetraphosphate synthetase, GARS, GlyRS, Glycine-tRNA ligase, SMAD1

Gene ID: 2617, 9606

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process