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GNA12 antibody (Guanine Nucleotide Binding Protein (G Protein) alpha 12) (Ser67)

Details for Product anti-GNA12 Antibody No. ABIN360476, Supplier: Log in to see
Antigen
  • AI414047
  • AI504261
  • Galpha12
  • gep
  • gna12
  • gna12l
  • NNX3
  • RMP
Epitope
Ser67
14
9
4
2
2
2
2
1
1
Reactivity
Human
38
22
18
2
1
1
1
1
1
Host
Rabbit
40
1
1
Clonality
Polyclonal
Conjugate
This GNA12 antibody is un-conjugated
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
29
14
12
4
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S67 of human GNA12.
Isotype Ig
Specificity This antibody reacts to GNA12.
Purification Protein A column, followed by peptide affinity purification
Alternative Name G Protein Subunit alpha 12 / GNA12 (GNA12 Antibody Abstract)
Background Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.Synonyms: G alpha-12, Guanine nucleotide-binding protein subunit alpha-12
Gene ID 2768, 9606
UniProt Q03113
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-GNA12 antibody (Guanine Nucleotide Binding Protein (G Protein) alpha 12) (Ser67) (ABIN360476) anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Ser67) antibody
Background publications Krakstad, Ardawatia, Aragay: "A role for Galpha12/Galpha13 in p120ctn regulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 28, pp. 10314-9, 2004 (PubMed).

Suzuki, Nakamura, Mano, Kozasa: "Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 733-8, 2003 (PubMed).

Yamaguchi, Katoh, Negishi: "N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 14936-9, 2003 (PubMed).

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).