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PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (N-Term)

Details for Product anti-PIP5K1C Antibody No. ABIN360480, Supplier: Login to see
Antigen
  • MGC130766
  • PIP5K1C
  • pip5k1a
  • zgc:110576
  • si:dkey-29i9.1
  • AI115456
  • AI835305
  • Pip5kIgamma
  • LCCS3
  • PIP5K-GAMMA
  • PIP5Kgamma
  • PIPKIg_v4
Alternatives
anti-Human PIP5K1C antibody for ELISA
Epitope
N-Term
10
8
4
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
38
6
5
2
Host
Rabbit
33
6
Clonality
Polyclonal
Conjugate
This PIP5K1C antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
27
13
3
2
1
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PIP5K1G.
Isotype Ig
Specificity This antibody reacts to PIP5Ki gamma.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name PIP5K1C (PIP5K1C Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.Synonyms: KIAA0589, PIP5K1-gamma, PIP5KIgamma, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, PtdIns(4)P-5-kinase 1 gamma
Gene ID 23396, 9606
UniProt O60331
Pathways PI3K-Akt Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (N-Term) (ABIN360480) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (N-Term) antibody
 image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (N-Term) (ABIN360480) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (N-Term) antibody (Image 2)
Background publications Ling, Doughman, Firestone et al.: "Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions." in: Nature, Vol. 420, Issue 6911, pp. 89-93, 2002 (PubMed).

Di Paolo, Pellegrini, Letinic et al.: "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin." in: Nature, Vol. 420, Issue 6911, pp. 85-9, 2002 (PubMed).

Ishihara, Shibasaki, Kizuki et al.: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998 (PubMed).