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GAK antibody (C-Term)

GAK Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360521
  • Target See all GAK Antibodies
    GAK (Cyclin G Associated Kinase (GAK))
    Binding Specificity
    • 15
    • 11
    • 9
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 66
    • 34
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 4
    Rabbit
    Clonality
    • 64
    • 2
    Polyclonal
    Conjugate
    • 28
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAK antibody is un-conjugated
    Application
    • 60
    • 39
    • 31
    • 13
    • 13
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to GAK.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GAK.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GAK Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    GAK (Cyclin G Associated Kinase (GAK))
    Alternative Name
    GAK (GAK Products)
    Synonyms
    GAK antibody, DKFZp469F1313 antibody, gak antibody, MGC172462 antibody, si:dkeyp-1e8.1 antibody, DNAJ26 antibody, DNAJC26 antibody, D130045N16Rik antibody, cyclin G associated kinase antibody, GAK antibody, gak antibody, Gak antibody
    Background
    GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.Synonyms: Cyclin G-associated kinase
    Gene ID
    2580
    NCBI Accession
    NP_005246
    UniProt
    O14976
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