PTPRG antibody (Middle Region)

Catalog No. ABIN360739

Product Details anti-PTPRG Antibody

Target: PTPRG (Protein tyrosine Phosphatase, Receptor Type, G (PTPRG))

Binding Specificity: Middle Region

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRG antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PTPgamma.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PTPgamma.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PTPRG

Target: PTPRG (Protein tyrosine Phosphatase, Receptor Type, G (PTPRG))

Alternative Name: PTPRG / PTPG (PTPRG Products)

Synonyms: HPTPG antibody, PTPG antibody, R-PTP-GAMMA antibody, RPTPG antibody, 5430405N12Rik antibody, AW046354 antibody, AW549872 antibody, RPTPgamma antibody, Ptpg antibody, protein tyrosine phosphatase, receptor type G antibody, protein tyrosine phosphatase, receptor type, G antibody, PTPRG antibody, Ptprg antibody

Background: PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.Synonyms: Receptor-type tyrosine-protein phosphatase gamma

Gene ID: 5793, 9606

UniProt: P23470