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PPM1F antibody (C-Term)

PPM1F Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360801
  • Target See all PPM1F Antibodies
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    Binding Specificity
    • 10
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 53
    • 2
    • 1
    Human
    Host
    • 47
    • 6
    Rabbit
    Clonality
    • 50
    • 3
    Polyclonal
    Conjugate
    • 24
    • 6
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPM1F antibody is un-conjugated
    Application
    • 38
    • 29
    • 25
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PPM1F.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PPM1F.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PPM1F Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    Alternative Name
    Protein Phosphatase 1F / PPM1F (PPM1F Products)
    Synonyms
    1110021B16Rik antibody, 4933427B07Rik antibody, CaMKPase antibody, Popx2 antibody, mKIAA0015 antibody, CAMKP antibody, FEM-2 antibody, POPX2 antibody, hFEM-2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1F antibody, protein phosphatase 1F (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1F antibody, PPM1F antibody, Ppm1f antibody
    Background
    PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.Synonyms: Ca(2+)/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase, CaMKPase, KIAA0015, POPX2, Partner of PIX 2, Protein fem-2 homolog
    Gene ID
    9647, 9606
    UniProt
    P49593
    Pathways
    Positive Regulation of Endopeptidase Activity
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