PPP3CC antibody (C-Term)

Catalog No. ABIN360813

Product Details anti-PPP3CC Antibody

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Binding Specificity: AA 480-509, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes PPP3CC.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 480~509 amino acids from the C-terminal region of Human PPP3CC.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Alternative Name: PPP3CC / CALNA3 (PPP3CC Products)

Synonyms: CALNA3 antibody, CNA3 antibody, PP2Bgamma antibody, Calnc antibody, ppp3cc antibody, sb:cb767 antibody, si:dkey-21k4.5 antibody, calna3 antibody, cna3 antibody, pp2bgamma antibody, im:7163784 antibody, zgc:158685 antibody, protein phosphatase 3 catalytic subunit gamma antibody, protein phosphatase 3, catalytic subunit, gamma isoform antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, a antibody, protein phosphatase 3, catalytic subunit, gamma isozyme antibody, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, b antibody, PPP3CC antibody, Ppp3cc antibody, ppp3cca antibody, ppp3cc antibody, ppp3cc.L antibody, ppp3ccb antibody

Background: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma

Gene ID: 5533

NCBI Accession: NP_005596

UniProt: P48454

Pathways: RTK Signaling, WNT Signaling, VEGF Signaling, BCR Signaling