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PPP6C antibody (N-Term)

PPP6C Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360838
  • Target See all PPP6C Antibodies
    PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
    Binding Specificity
    • 10
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 50
    • 10
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 3
    • 3
    Rabbit
    Clonality
    • 47
    • 3
    Polyclonal
    Conjugate
    • 26
    • 6
    • 5
    • 5
    • 4
    • 4
    This PPP6C antibody is un-conjugated
    Application
    • 42
    • 34
    • 14
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PPP6C.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PPP6C.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PPP6C Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
    Alternative Name
    PPP6C (PPP6C Products)
    Synonyms
    PP6 antibody, PP6C antibody, 2310003C10Rik antibody, zgc:56227 antibody, ppp6c antibody, PPP6C antibody, pp6 antibody, MGC114734 antibody, DDBDRAFT_0168786 antibody, DDBDRAFT_0185210 antibody, DDB_0168786 antibody, DDB_0185210 antibody, CG12217 antibody, DmPpV-6A antibody, Dmel\\CG12217 antibody, PPPV6A antibody, PPV antibody, PPV 6A antibody, Ppv antibody, dPP6 antibody, protein phosphatase 6 catalytic subunit antibody, protein phosphatase 6, catalytic subunit antibody, protein phosphatase 6, catalytic subunit L homeolog antibody, serine/threonine-protein phosphatase 6 catalytic subunit antibody, Protein phosphatase V antibody, PPP6C antibody, Ppp6c antibody, ppp6c antibody, ppp6c.L antibody, ppp6C antibody, PpV antibody
    Background
    PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.Synonyms: PP6C, PPP6, Serine/threonine-protein phosphatase 6 catalytic subunit
    Gene ID
    5537
    NCBI Accession
    NP_001116827
    UniProt
    O00743
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