Lamin B1 antibody

Catalog No. ABIN360850

Product Details anti-Lamin B1 Antibody

Target: Lamin B1 (LMNB1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificity: The antibody Clone 119D5-F1 reacts with an epitope located C-terminal of residue 231 in Lamin B1.

Purification: Purified

Immunogen: Purified Rat liver lamins.

Clone: 119D5-F1

Isotype: IgG1

Application Details

Application Notes: Immunocytochemistry (1: 100 - 1: 200 with avidin-biotinylated horseradish peroxidasecomplex (ABC) as detection reagent). Immunoblotting (1: 100 - 1: 1000). Flow cytometry (1: 100 - 1: 200). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin-B1 (LMNB1) (LMNB1 Products)

Synonyms: MGC52550 antibody, Lamin-L(I) antibody, lamin-b antibody, lmn antibody, lmn2 antibody, lmnb antibody, LMNB1 antibody, ADLD antibody, LMN antibody, LMN2 antibody, LMNB antibody, fc06g01 antibody, wu:fc06g01 antibody, lamin B1 L homeolog antibody, lamin B1 antibody, lmnb1.L antibody, lmnb1 antibody, LMNB1 antibody, Lmnb1 antibody

Background: Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane.Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2.Synonyms: LMN2, LMNB, LMNB-1, LMNB1, Lamin-B1, Nuclear Envelope Marker

Molecular Weight: 67 kDa (Predicted)

Gene ID: 4001

NCBI Accession: NP_005564

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis