EGFL7 antibody

Catalog No. ABIN360963

Product Details anti-EGFL7 Antibody

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGFL7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognizes VE-Statin/EGFL7.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography.

Immunogen: Highly pure recombinant human VE-Statin/EGFL-7

Isotype: IgG

Application Details

Application Notes: Western Blot (1-5 μg/mL) using the appropriate secondary reagents to detect HumanVE-Statin/EGFL-7. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water/PBS to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Preservative: Without preservative

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for EGFL7

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Alternative Name: EGFL7 (EGFL7 Products)

Synonyms: egfl7 antibody, MGC53105 antibody, EGFL7 antibody, zgc:136669 antibody, zgc:152804 antibody, zneu1 antibody, xegfl7 antibody, MGC147423 antibody, VE-statin antibody, Zneu1 antibody, NEU1 antibody, RP11-251M1.2 antibody, VE-STATIN antibody, ZNEU1 antibody, EGF like domain multiple 7 S homeolog antibody, EGF like domain multiple 7 antibody, EGF-like-domain, multiple 7 antibody, EGF-like domain 7 antibody, egfl7.S antibody, EGFL7 antibody, egfl7 antibody, Egfl7 antibody

Background: EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.Synonyms: EGF like protein 7, EGF-like protein 7, Epidermal growth factor-like protein 7, MEGF7, Multiple EGF-like domains protein 7, Multiple epidermal growth factor-like domains protein 7, NOTCH4-like protein, PRO1449, UNQ187, VE-statin, Vascular endothelial statin, Zneu1

Gene ID: 51162

NCBI Accession: NP_057299

UniProt: Q9UHF1