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BH3 Interacting Domain Death Agonist (BID) antibody

Antigen

BH3 Interacting Domain Death Agonist (BID)

Synonyms FP497, MGC15319, MGC42355, AI875481, AU022477, 2700049M22Rik, BID, MGC140420, bid, si:ch211-238n5.6, xbid, fp497, DKFZp469E066
Clonality Monoclonal (4D3)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives ELISA, Western Blotting (WB)
Catalog no. ABIN361014
Quantity 50ul  (1mg/ml)  (Variants)
Price 300.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information

Alternative name BID
Immunogen Recombinant human BID (1-195aa), Accession / GI number: NP_001187
Isotype IgG1, kappa chain  (Matching secondary antibodies)
Clone 4D3
Description BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Synonyms: BH3 interacting domain death agonist isoform 2

Application Details

Application Notes Recommended dilution 1:1000
Concentration 1mg/ml
Purification The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Buffer In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Storage Store at -20°, Aliquot to avoid repeated freezing and thawing.
Research Area Cancer
Restrictions For Research Use only

Alternatives

Alternatives for antigen "BH3 Interacting Domain Death Agonist (BID)", type "Antibodies"
Hosts Rabbit (64), Mouse (16), Goat (7), Rat (4)
Reactivities Human (78), Mouse (Murine) (42), Rat (Rattus) (23), Dog (Canine) (5), Chicken (2), Pig (Porcine) (2), Cow (Bovine) (1), Sheep (Ovine) (1)
Applications Western Blotting (WB) (74), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Flow Cytometry (FACS) (24), Immunoprecipitation (IP) (23), Immunofluorescence (IF) (21), Enzyme Immunoassay (EIA) (20), ELISA (19), Immunohistochemistry (IHC) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (5), pSer65 (2), BH3 Domain Specific (1), S61 (1), pS65 (1), pSer61 (1)