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Antibodies
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
| Antigen |
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| Synonyms |
LCA, LY5, B220, CD45, T200, CD45R, GP180, Lca, RT7, L-CA, PTPRC, si:dkeyp-47c5.1 |
| Clonality |
Monoclonal (2H12) |
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Host
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Reactivity
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Human (247), Mouse (Murine) (186), Rat (Rattus) (60), Dog (Canine) (32), Chicken (27), Cow (Bovine) (18), Sheep (Ovine) (15), Pig (Porcine) (10), Cat (Feline) (6), Bird (Avian) (5), Goat (3), Primate (3), Guinea Pig (2), Rabbit (2), Monkey (1)
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Application
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Flow Cytometry (FACS) (480), Immunohistochemistry (Frozen Sections) (IHC (fro)) (137), Immunoprecipitation (IP) (109), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (83), Western Blotting (WB) (47), Immunohistochemistry (IHC) (24), Immunofluorescence (IF) (19), ELISA (15), Immunocytochemistry (ICC) (9), Enzyme Immunoassay (EIA) (8), Cytotoxicity Test (CyTox) (4), Functional Studies (Func) (2), Radioimmunoassay (RIA) (2), To be determined by user (TBD) (1)
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| Catalog no. |
ABIN361025 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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CD45
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Immunogen
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Recombinant CD45, Accession / GI number: NM_002838
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Isotype
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TBD, kappa chain
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Clone
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2H12
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Description
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CD45 belongs to a family of heavily glycosylated, high molecular weight transmembrane glycoproteins expressed on all cells of haematopoietic origin. Structurally heterogeneous, CD45 consists of a family of eight isoforms ranging from 180,000 to 220,000 MW generated by alternative splicing of three exons differentially expressed on subpopulation of lymphocytes. CD45 protein tyrosine phosphatase activity plays a central role in T-cell activation. CD45 plays an important role in signal transduction inhibition or upregulation of various immunological functions.
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Restrictions
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For Research Use only
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Alternatives for antigen "Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)", type "Antibodies"
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Hosts
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Mouse (330), Rat (207), Rabbit (18)
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Reactivities
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Human (247), Mouse (Murine) (186), Rat (Rattus) (60), Dog (Canine) (32), Chicken (27), Cow (Bovine) (18), Sheep (Ovine) (15), Pig (Porcine) (10), Cat (Feline) (6), Bird (Avian) (5), Goat (3), Primate (3), Guinea Pig (2), Rabbit (2), Monkey (1)
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Applications
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Flow Cytometry (FACS) (480), Immunohistochemistry (Frozen Sections) (IHC (fro)) (137), Immunoprecipitation (IP) (109), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (83), Western Blotting (WB) (47), Immunohistochemistry (IHC) (24), Immunofluorescence (IF) (19), ELISA (15), Immunocytochemistry (ICC) (9), Enzyme Immunoassay (EIA) (8), Cytotoxicity Test (CyTox) (4), Functional Studies (Func) (2), Radioimmunoassay (RIA) (2), To be determined by user (TBD) (1)
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Conjugates
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FITC (86), PE (55), Biotin (54), APC (28), RPE (14), SPRD (8), Cy5 (6), PE,Cy5 (5), Cy5,PE (4), Cy5.5,PE (4), PE,Cy7 (4), Alexa Fluor 488 (3), Cy7,PE (3), PE,Cy5.5 (3), PerCP (3), APC,Cy7 (2), Alexa Fluor 647 (2), Cy5.5 (2), PE,DY647 (2), Pacific Blue (2), RPE,Cy5 (2), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 700 (1), PE,DY590 (1), PE,Texas Red (TR) (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1)
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Epitopes
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C-Term (3)
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Alternatives 
