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Antibodies
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anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibody
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibody
| Antigen |
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| Synonyms |
ICH1, NEDD2, CASP-2, ICH-1L, ICH-1L/1S, ICH-1, Nedd2, Caspase-2, xCaspase-2 |
| Clonality |
Monoclonal (1C10) |
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Host
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Reactivity
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Application
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Western Blotting (WB) (48), Flow Cytometry (FACS) (22), Immunofluorescence (IF) (21), ELISA (18), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunoprecipitation (IP) (7), Immunohistochemistry (IHC) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN361036 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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Caspase-2
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Immunogen
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Recombinant Caspase-2 , Accession / GI number: NP_116764
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Isotype
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TBD, kappa chain
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Clone
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1C10
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Description
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The caspase family of cystein proteases functions as fundamental effectors in apoptosis. These enzymes participate in a cascade that is triggered in response to proapoptotic signals and culminates in cleavage of a set of proteins, resulting in disassembly of the cell. Caspase-2, initially described as NEDD2/ICH1, was identified as a protein related to the Caenorhabditis elegans cell death protein CED-3 and mammalian interleukin-1beta-converting enzyme which is highly expressed in embryonic brain and down-regulated in adult brain.
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Application Notes
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Recommended dilution 1:500
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2)", type "Antibodies"
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Hosts
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Rabbit (51), Mouse (12), Rat (4)
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Reactivities
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Human (64), Mouse (Murine) (33), Rat (Rattus) (27), Cow (Bovine) (16), Horse (Equine) (15), Pig (Porcine) (15), Rabbit (15), Dog (Canine) (4)
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Applications
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Western Blotting (WB) (48), Flow Cytometry (FACS) (22), Immunofluorescence (IF) (21), ELISA (18), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunoprecipitation (IP) (7), Immunohistochemistry (IHC) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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N-Term (2), Ab-157 (1), Center (1), cleaved (1), p18 Cleaved-Gly170 (1), p18 Cleaved-Thr325 (1), pSer157 (1)
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Alternatives 
