Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) antibody

Antigen: Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A)

Synonyms: EPM2, MELF

Clonality: Monoclonal (K2A3)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN361048

Additional Information

Alternative name: EPM2A

Immunogen: Recombinant human EPM2A (243-331aa), Accession / GI number: NP_005661

Isotype: IgG1, kappa chain  (Matching secondary antibodies)

Clone: K2A3

Description: Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy. Synonyms: Laforin isoform a

Application Details

Application Notes: Recommended dilution 1:1000

Concentration: 1mg/ml

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Storage: Store at -20°, Aliquot to avoid repeated freezing and thawing.

Research Area: Enzymes

Restrictions: For Research Use only

Images

anti-Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) antibody