Flip antibody
| Antigen |
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| Clonality |
Monoclonal (5D8) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361055 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Immunogen
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Recombinant human FLIP (1-376aa) , Accession / GI number: NP_003870
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Isotype
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IgG3, kappa chain (Matching secondary antibodies)
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Clone
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5D8
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Description
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FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1). Synonyms: CASP8 and FADD-like apoptosis regulator isoform 1
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Application Notes
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Recommended dilution 1:500
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Signaling
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Restrictions
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For Research Use only
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Alternatives for antigen "Flip", type "Antibodies"
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Hosts
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Rabbit (40), Mouse (2)
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Reactivities
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Human (42), Mouse (Murine) (36), Rat (Rattus) (36), Cow (Bovine) (35), Dog (Canine) (34), Rabbit (34), Pig (Porcine) (31), Horse (Equine) (19), Chicken (15)
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Applications
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Flow Cytometry (FACS) (36), Immunofluorescence (IF) (36), ELISA (8), Western Blotting (WB) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunoprecipitation (IP) (4), Immunoelectron Microscopy (IEM) (2)
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Conjugates
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Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
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