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Antibodies
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anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) antibody
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) antibody
| Antigen |
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| Synonyms |
CD305, LAIR-1, Lair-1, mLair-1, BB115266, D7Bwg0421e, 5133400O11Rik |
| Clonality |
Monoclonal (Lc12) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361089 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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LAIR-1
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Immunogen
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Recombinant LAIR-1, Accession / GI number: NP_068352
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Isotype
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TBD, kappa chain
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Clone
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Lc12
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Description
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Reacts with extracellular domain of the LAIR-1, a member of the leukocyte-associated Ig like receptor family. The LAIR-1 is a transmembrane glycoprotein(~32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells. LAIR-1 recruits SHP-1 and SHP-2 tyrosine phosphatases upon activation, and cross-linking of the LAIR-1 molecule on NK cells results in strong inhibition of NK cell-mediated cytotoxicity.
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Immunology
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Restrictions
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For Research Use only
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Alternatives for antigen "Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1)", type "Antibodies"
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Hosts
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Mouse (22), Goat (2), Rabbit (1)
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Reactivities
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Human (28)
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Applications
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Western Blotting (WB) (21), Flow Cytometry (FACS) (20), Enzyme Immunoassay (EIA) (6), ELISA (5), Immunoprecipitation (IP) (5), ELISA (Detection) (4), Functional Studies (Func) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2)
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Conjugates
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Biotin (2), FITC (2), PE (2)
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Alternatives 
