NRG1(HRG-Beta3) antibody
| Antigen |
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| Clonality |
Monoclonal (K1G13) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361097 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Immunogen
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Recombinant human NRG1 isoform HRG-beta3 (20-241aa), Accession / GI number: NP_039252
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Isotype
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IgG1, kappa chain (Matching secondary antibodies)
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Clone
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K1G13
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Description
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Neuregulin1 (NRG1) is one of four proteins in the neuregulin family that act on the Epidermal growth factor receptor (EGFR) family of receptors. NRG1 was originally identified as a 44 kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In many brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. This variant (HRG-beta3) of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines. Synonyms: neuregulin 1 isoform HRG-beta3
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Application Notes
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Recommended dilution 1:1000
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "NRG1(HRG-Beta3)", type "Antibodies"