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Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B) antibody
| Antigen | Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B) |
| Synonyms | CLMF, NKSF, CLMF2, NKSF2, IL-12B, p40, Il-12b, Il12p40, Il-12p40, Il12, IL12B, IL12A, IL-12p40, IL-12, il12b, IL-12 p40, MGC152789, il12p40.b, zgc:152789, IL-12.p40, Il12b, LOC100217488 |
| Clonality | Monoclonal (AT1D6) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Rat (Rattus) |
| Application |
Alternatives ELISA, Western Blotting (WB)
|
| Catalog no. | ABIN361135 |
| Quantity | 50ul (1mg/ml) (Variants) |
| Price | 300.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | IL12B |
| Immunogen | Recombinant human IL12B (23-328aa) purified from E. coli, Accession / GI number: NP_002178 |
| Isotype | IgG1, kappa chain (Matching secondary antibodies) |
| Clone | AT1D6 |
| Description | IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is responsible for the differentiation of naive CD4+T cells into type 1 helper T cells (Th1) that produce interferon-gamma (IFN-gamma). Expression of STAT 4, a signal transduction molecule important in cytokine-induced gene expression, appears central to IL-12 induced Th1 production of IFN-gamma. It also activates production of tumor necrosis factor alpha (TNF alpha) from T and natural killer cells. IL-12 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Synonyms: Interleukin 12B precursor |
Application Details
| Application Notes | Recommended dilution 1:1000 |
| Concentration | 1mg/ml |
| Purification | The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography |
| Buffer | In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide |
| Storage | Store at -20°, Aliquot to avoid repeated freezing and thawing. |
| Research Area | Hormones, Cytokines |
| Restrictions | For Research Use only |
Images
| anti-Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B) antibody |
Alternatives
Alternatives for antigen "Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B)", type "Antibodies"
| Hosts | Mouse (2), Goat (1) |
| Reactivities | Human (5), Rat (Rattus) (2), Mouse (Murine) (1) |
| Applications | ELISA (6), Western Blotting (WB) (6) |
