Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) antibody

Antigen: Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1)

Synonyms: NFAT2, NFATc, NF-ATC, MGC138448, NF-ATc, Nfatcb, AI449492, AV076380, 2210017P03Rik, nfat2, nfatc, nf-atc, MGC82799, NFATC1, NFAT, NF-ATc1, si:ch211-198c22.2, MGC146167

Clonality: Monoclonal (AT1C3)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN361141

Additional Information

Alternative name: NFATc1

Immunogen: Recombinant human NFATc1 (428-716aa) purified from E. coli, Accession / GI number: NP_765978

Isotype: IgG2a, kappa chain  (Matching secondary antibodies)

Clone: AT1C3

Description: Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1(NFATc1) is a component of the nuclear factor of activated T cells DNA-binding transcription complex which consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. This protein plays a main role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription and functions as a major molecular target for the immunosuppressive drugs such as cyclosporine A. NFATc1 is expressed in most human primary lymphocytes and mature human T- and B-cell neoplasms. Synonyms: nuclear factor of activated T-cells, cytosolic component 1 isoform A

Application Details

Application Notes: Recommended dilution 1:1000

Concentration: 1mg/ml

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Storage: Store at -20°, Aliquot to avoid repeated freezing and thawing.

Research Area: Signaling

Restrictions: For Research Use only

Images

anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) antibody