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Antibodies
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anti-Von Hippel-Lindau Tumor Suppressor (VHL) antibody
Von Hippel-Lindau Tumor Suppressor (VHL) antibody
| Antigen |
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| Synonyms |
RCA1, VHL1, HRCA1, Vhlh, BcDNA:RH61560, VHL, d-VHL, dVHL, dmVHL, Dmel\CG13221, CG13221, rca1, vhl1, hrca1, zgc:158722, DKFZp469K2019 |
| Clonality |
Monoclonal (52A11) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361172 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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VHL
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Immunogen
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Recombinant VHL, Accession / GI number: NP_000542
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Isotype
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TBD, kappa chain
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Clone
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52A11
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Description
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Von Hippel-Lindau disease (VHL) is a dominant inherited syndrome characterized by the predisposition to develop various kinds of benign and malignant tumors, including clear cell renal carcinomas, pheochromocytomas and hemangioblastomas of the central nervous system and retina. VHL syndrome is caused by germline mutation in the VHL tumor suppressor, and VHL tumors are associated with loss or mutation of the remaining wild-type allele. VHL has two domains: a roughly 100-residue NH2-terminal domain rich in beta sheet (beta-domain) and a smaller a-helical domain (a-domain), held together by two linkers and a polar interface. VHL protein is also involved in the degradation of hypoxia-inducible factor (HIF).
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Application Notes
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Recommended dilution 1:500
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Hormones, Cytokines
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Restrictions
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For Research Use only
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Alternatives for antigen "Von Hippel-Lindau Tumor Suppressor (VHL)", type "Antibodies"
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Hosts
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Rabbit (32), Mouse (24), Goat (7), Chicken (1)
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Reactivities
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Human (53), Mouse (Murine) (10), Dog (Canine) (4), Rat (Rattus) (4)
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Applications
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Western Blotting (WB) (56), ELISA (15), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), ELISA (Detection) (3), Immunohistochemistry (IHC) (2), Immunoprecipitation (IP) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Biotin (6), HRP (3)
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Epitopes
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C-Term (2), N-Term (2)
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Alternatives 
